The European Chemicals Agency (ECHA) has been reviewing 2-ethylhexanoic acid (2-EHA) as a substance that possibly results in reproductive toxicity and potential neurodevelopmental toxicity. ECHA has now concluded that the product is considered safe with risk mitigation measures in place, and it is no longer under consideration for additional classification and labeling. 2-EHA will remain classified as Reproductive Toxicity Category 2, meaning consumer use should be restricted and some risk mitigating measures need to be taken into account when it is used at production facilities. Andreas Nilsson, product manager for Perstorp (the world’s largest producer of 2-EHA), stated,“Despite 2-EHA being the most accessible and cost-effective carboxylic acid available, the suspicion caused the market sentiment to sway towards replacement of 2-EHA in some cases. These studies now make 2-EHA the best-investigated carboxylic acid. We are very happy that these suspicions have been lifted.“ 2-EHA (2-ethylhexanoic acid) is widely used in esters for PVB film plasticizers and synthetic lubricants, in production of metal soaps for paint driers, in automotive coolants and PVC stabilizers. Other application areas include wood preservatives, catalyst for polyurethane and in pharmaceuticals. Yearly production amounts to almost 300.000 tons.